Biodegradation of Lycopene on AFB1 Naturally Contaminated Feed and Their Residue in Liver and Muscles Tissues of Local Male Rabbits

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Mohamed Rasol Mahdi, Adil Jabbar Atiyah

Abstract

Mycotoxins are secondary fungalmetabolites that are chronic exposure ledtoresi due in biological fluids This study was carried out to find  concentration of AFB1 in liver and muscle, and to study the impact of mycotoxinson effects on performance after addition  of lycopene (LYC)   in  contaminated feed on malerabbits.


Twenty-eight local maleRabbits at age of 4-5monthswithanaveragebodyweight of 1340 gm. which are distributedbythebodyweight in fourgroups of sevenanimals. the control groupwerereceived basal dietonly( c ) ,whileT1,T2,T3groupsreceivedbasal diet y ralnatcontaminatedby AFB1( 20.15 μg /kg Diet) exceptthe(T1),T2 and T3wereLycopene 20 mg/ head  and 40 mg/head  respectively Cholesterol is significantly (P<0.05) decrease in e in T2 , T3 group compared with other groups .HDL showed higher level in T2 , T3 compared with T1 and control groups, significantly (P<0.05) decrease in LDL in T2 , T3 groups compared with T1 and control groups . Creatinine showed no significant change in all groups, and  no change in AST, ALT enzymes.


The average concentration of AFB1 (μg/kg) was higher in muscle tissue than in liver tissue. Muscle and liver tissue control groups were not updated. The AFB1 concentration in the liver tissue (140, 2.3, 0.25) ppb appeared sequently (T1, T2, T3). In addition. While the Residues of AFB1 seen in muscle (203.1, 6.8, 0.62 ) ppb (T1, T2, T3), compared with AFB1 0.125 ppb.


These findings indicate that supplementation of Lycopene in rabbit feeding will decreaseresidue the liver and  muscle tissues' and maintain a healthy condition for rabbits..

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How to Cite
Mohamed Rasol Mahdi, Adil Jabbar Atiyah. (2021). Biodegradation of Lycopene on AFB1 Naturally Contaminated Feed and Their Residue in Liver and Muscles Tissues of Local Male Rabbits. Annals of the Romanian Society for Cell Biology, 25(2), 385–393. Retrieved from http://annalsofrscb.ro/index.php/journal/article/view/960
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