Formation, Characterization of Some New Coii, Cuii, Ni II, Au Iiipotassium (2-Carboxyphenyl) (2,3-Dimethylphenyl) Carbamodithioate complexes and Study Their Biological Activity

Abstract

A new ligand (potassium (2-carboxyphenyl)(2,3-dimethylphenyl)carbamodithioate) is being synthesized and characterized. which has two sulfur donor atoms in it.The ligand was made by reacting one equivalent of carbon disulfide and 2-((2,3-dimethylphenyl)amino)benzoic acid for4 hours in ethanol (as a solvent) in the presence of an alkali base (KOH). The FT-IR , ¹HNMR, ¹³C-NMR , (C.H.N.S), UV-visible, and ESI-mass range, as well as the melting point, were used to describe the dithiocarbamate ligand.Four metal complexes are prepared by refluxing.The complexes were made by reacting two equivalents of potassium dithiocarbamate ligand with one equivalent metal salt for four hours in refluxing ethanol.For certain complexes, FT-IR, UV-Visible, molar conductivity, magnetic susceptibility, solubility of flammable atomic absorption spectroscopy, melting point, element microanalysis, and mass spectroscopy were used to characterize them.The biological effectiveness of the preparedithiocarbamate ligand and the complexes was investigated using the inhibition method in four different bacteria: two Gram positive and two Gram negative bacteria, as well as one pathogenic fungus.