Study of the Effectiveness of the Use of Monoclonal Antibodies in Rheumatological Diseases

Abstract

The study included 41 patients diagnosed with RA (24), Ankylosing spondylitis (3), Takayasu's disease (2), SLE (10), psoriatic arthritis (2), which were confirmed according to the ICD 10 classification. patients received basic therapy: methotrexate at a dose of 7.5–10 mg per week; three patients also received 7.5-10 mg of glucocorticosteroids per day. All patients also received non-steroidal anti-inflammatory drugs (NSAIDs) in adequate daily doses. Nevertheless, against the background of the therapy, a consistently high activity of the disease was noted. Twenty-one patients received Tocilizumab infusions.

The aim of the study was to study the effectiveness of using monoclonal antibodies in rheumatological diseases.