The Effect of Abortion, Use of Hormonal Contraception, First Age of Pregnancy and Parity on the Incidence of Breast Cancer at the Riau Referral Hospital

Abstract

Background: Breast cancer is a cancer in women with a high percentage of 34% of all cancers and 12.8% of sufferers causing death. It is estimated that breast cancer will reach 3.2 million by 2050. In 2018, 365 out of 580 cases of cancer treated were breast cancer. There was an increase in outpatient visits at the oncology polyclinic in 2016 - 2018 from 1286 to 2495

Objective: This study aims to determine the level of correlation between, history of abortion, use of hormonal contraception, age at first birth and parity with the incidence of breast cancer.

Methods: This research is quantitative analytic observational with a case control design by taking medical register data and interviews from research respondents. This research was conducted at ArifinAchmad Referral Hospital, Riau Province on July 2-12, 2019. There were 324 new patients and old patients with Anatomical Pathology (PA) results of breast tissue as breast cancer.

Result: The results of the omnibus test of model coefficient = 0.000 ,. Nagelkerke R Square value = 0.242, which means that there is a significant relationship between abortion history, history of use of hormonal contraceptives, age at first birth and parity with the incidence of breast cancer 24.2%. p = 0.035), history of using hormonal contraceptives (p = 0.00), age at first birth (p = 00.1), number of children (p = 0.042)

Discussion: From the multivariate analysis, it was found that there was an increase in the incidence of breast cancer in women with: history of abortion was 3.7 times; a history of using hormonal contraception 5.4 times; age of giving birth to their first child over 35 years is 3.0 times, while nulliparous women have 2.3 times the risk