Rapid and Cost Effective COVID-19 Diagnostic Test Kit

Abstract

COVID-19 or Corona Virus disease spreading since December 2019 starting from Wuhan China has now become a pandemic throughout the globe. For early detection of the infected persons prior to the onset of the disease has become necessary to stop the spreading of this communicable disease. The process of testing of respiratory COVID-19 and the associated SARS- COV-2 virus is proved to be possible only by the detection of antibody produced due to response to the infection. This process of antibody detection can be used for both diagnosis and population surveillance. The testing of generated antibodies due to SARS-COV-2 are antibody isotopes that are to be detected are IgG and IgM . Due to having novel antigens the first responding antigen antibody interactions was IgM. Antibodies that show higher affinity for more specifically binding capable antigens leading to proper immune response is IgG. Due to the infectious reactions IgG antibodies are produced.  Positiveness of a sample is considered if both IgG and IgM are present. Whole blood, serum or plasma specimens are used for membrane based immunoassay in a qualitative IgG and IgM test kit. The principle for the testing is same that of a HCG pregnancy test where human glycoprotein is assayed in a rapid chromatographic way. The mentioned process is very useful for mass detection of the COVID-19 infected population in a minimum time and is also safe for the laboratory technicians as it can easily be done without getting infected if proper physical barrier are taken personally.