Covid-19 And Periodontium- An Interplay Cytokine Connection- A Review

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Janani M, Jaideep Mahendra, PrashanthiSankar, AmbalavananNamasivayam


Periodontal diseases include the category of diseases involving the inflammation process which affects the tooth supporting structures resulting in bone resorption, tooth loss on later stages which might on a longer run be able to be associated with systemic complications. There are varying systemic disorders and conditions being reported with periodontal disease which include diabetes, hypertension, cardiovascular diseases, obesity although the complete association between the risk factors shared has not been explored completely. The outbreak of severe acute respiratory syndrome coronavirus (SARS-CoV) signaled a cross species transmission which spread across the globe in the beginning of 21st century. As COVID-19 diseaseshares a common mechanism of triggering the dysbiosis and inflammatory reaction as periodontal disease, there can be possible associationbetween periodontal diseases and COVID-19 disease which on further research could establish a strong relation between COVID-19 and periodontal disease. This article aims to review the possible connecting mechanism linking periodontal disease and COVID-19.


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Janani M, Jaideep Mahendra, PrashanthiSankar, AmbalavananNamasivayam. (2020). Covid-19 And Periodontium- An Interplay Cytokine Connection- A Review. Annals of the Romanian Society for Cell Biology, 85–91. Retrieved from