Liver Transplantation and immunosuppressants in Current Scenario : A Short Review

Abstract

Liver transplantation (LT) is Standard therapy for patients who are suffering from end-stage liver disease and their complications. After the transplantation the graft can't live without immunosuppressants, Medication becomes part of their life thus it increases the survival rate of patients by preventing or reducing the rejection episodes . Although the therapy is mandatory on the same way it is associated with several adverse events like ong-term adverse effects of prolonged use of immunosuppressive agents such as malignancies, opportunistic infections, metabolic disorders, and other organ toxicities have now become a major concern, still calcineurine inhibitors stay as the backbone of the graft patients because of their better efficacy . Apart from the age category of people belong, if the patient is indeed for surgery can withstand the therapy, LT is recommended. Another unspoken area of therapy is the financial side, the surgery is very costly which is already known, Also the treatment after transplant also affects the patient financially.