Main Article Content
In the article, the authors revealed the latest modern data on the analysis of literature on the polymorphism of pro- and anti-inflammatory cytokine genes that are most significant in the development of bronchopulmonary diseases. It has been shown that the secretion of pro-and anti-inflammatory cytokines TNF-α, IL-4, IL-1b, IL-6, IL-10 can change in these diseases. The article analyzes the polymorphic properties of genes encoding cytokines, depending on the concentration of these molecules and the course of the disease.
A detailed study of the polymorphic properties of cytokine genes contributes to the development of criteria for predisposition to the development of recurrent bronchitis in children with lymphotic-hypoplastic diathesis and to substantiate the possibility of a new approach to therapy.