Fatigue The Most Unattended Non- Motor Symptom In Idiopathic Parkinson’s Disease – Review Report

Abstract

Background: -Fatigue being the most unrevealed, unattended symptoms among the non-motor symptoms, has shown to be the most disabling element in the road to recovery and have a greater impact on the quality of life among patients with Parkinson's disease. Yet the concept of fatigue is poorly studied. Objective: - The article reviews known evidence about fatigue prevailing in Parkinson’s Disease and outlines the importance of optimizing the qualitative assessment with a non-invasive biomarker and physical therapy intervention. Major findings: - This subjectively measured non-motor symptom greatly depends on the patient's response which varies from one person to person. A standard quantitative assessment is yet to be found to measure the level of fatigue pre and post-physical therapy intervention. It is often confused with cognitive or physical exertion. This has led to low-quality evidence or no proper treatment protocols Conclusion: -This study thus concludes that non-motor symptoms often resist recovery, among which fatigue is the most felt but not reported. Future studies are to be directed to focus on fatigue and more promising protocols to be studied for their frequency, duration, and application.