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This study was conducted on patients with hypertension and diabetes of both sexes in Salah al-Din Governorate. The study started from the beginning of December 2019 until the first of March 2020, and the study included 90 people divided into three groups. Blood samples were collected from the patients and healthy subjects and then serum was separated for subsequent tests.
This study aimed to obtain more clarification of some hormonal and immune changes in patients with hypertension and diabetes, and to know the effect of this increase on the changes in the concentrations of some hormones such as Renin, angiotensin-1, and Aldosterone, as well as studying the role of the immune marker osteopentin.The results of the study showed a "high significant increase (p ≤ 0.01) in the concentrations of the hormones Renin, angiotensin-1, and aldosterone in the blood serum of groups of hypertensive, hypertensive and diabetic patients compared with the control group. No significant differences were found in the concentration of the immune index. Osteopontine among all groups of hypertensive, hypertensive and diabetic patients, and of both sexes, compared with the control group.