Ige Level Correlation with H-Pylori Infection and Asthma

Abstract

Introduction

H-pylori are one of common infection in human. It is gram negative spiral bacteria.H-pylori bacteria can cause many presentations such as gastritis, peptic ulcer and some times end by gastric cancer. Immune response due to H-pylori infection primarily presented humoral and cellular response.

Aim of study:

To assess the association between immunoglobulin E level and asthma in one hand and H-pylori infection on another hand.

Method

A cross sectional study enrolled patients with gastric upset and dyspepsia.

Ninety six patients those completed the intended investigation.Antibody for H-pylori was evaluated for every patient.Measurement of serum LgE level was done.

Result

The mean age of enrolled patients was 46.2±10.4, with range 15-60 years. The male was constituent 62.3% and female was 37.7%.

The mean level of IgE in patients had been infected was 198.2±43.6 which is higher than level of non infected patients 87.1±23.8. Regarding asthma there were only four patients had history of asthma were infected by H-pylori which significant difference.

Conclusion

There were direct correlation between high IgE level H-pylori infection with inverse association between H-pylori and asthma.