A Case Series of De Novo Histoid Leprosy and Review of Literature

Abstract

Histoid leprosy is a bacillary rich leproma with abundant histoid bacillus having unique clinical, bacteriological and histopathological characteristics. It is a rare form of leprosy which usually manifests following monotherapy or drug resistance and rarely as de novo.It poses a challenge in diagnosis as it mimics a variety of dermatological conditions & in many cases it lacks the cardinal features like loss of sensation. Early Diagnosis and treatment of histoid leprosy is important as it might serve as a reservoir and source of community spread. In this article, we report a case series of this unique variant of leprosy and review of literature.