Frequency of Transfusion Transmitted Infection among Transfusion Dependent Beta Thalassemia Patients in District Headquarter Hospital Turbat Kech Baluchistan

Abstract

Objective

To estimate the frequency of transfusion transmittedinfection among transfusion dependent beta thalassemia patients in District Headquarter Hospital TurbatKech Baluchistan.

Methodology

This was a cross sectional study conducted in district headquarter hospital TurbatKech Baluchistan. All known diagnosed cases of beta thalsemia major, registered at District Headquarter Hospital Turbat, Kech, irrespective of their age, gender and transfused at least five unit of blood were included. Those who were not resident of District Kech Baluchistan were excluded from the study. 5ml of blood was drawn a aseptically using a 5 cc disposeable syringe and tested for HIV, HBV and HCV. SPSS v.22 was used for the statistical analysis purpose.

Results

The average age of 100 thalsemic patients was 8.58 _+ 6.68 years (minimum 1 maximum 4). The vast majority of the patients (80%) were under the age of ten. The male prevalence was found to be higher (60%) than the female preponderance (40 percent ). Hepatitis C infection was found to be reactive in the majority of patients (21%) followed by HIV (4%) and hepatitis B infection was shown to be reactive in one patient. When baseline parameters were compared to HIV, HBV, and HCV reactivity, only age (p-value 0.044) was shown to be substantially related with HBV infection, whereas all other factors were statistically insignificant (p-value>0.05).

Conclusion

In the District Headquarter Hospital TurbatKechBlauchistan, hepatitis C was the most common transfusion-transmitted infection among transfusion-dependent beta thalassemia patients, followed by HIV and hepatitis B.