Regular exercise in morning will balance internal metabolism avoiding many clinical diseases- A review

Abstract

The presence of obesity due to sedentary life style is alarming, leading to conditions such as metabolic diseases, diabetes, cancer and cardiovascular disease. The future is not good with the spread of physical inactivity  and irregular eating habits. Fasting and exercise are natural and inexpensive methods to help manage obesity- and overweight-related complications. There are different cells in our body and their energy sources are also different. Heart tissue need only Fats or Ketone bodies, Brain cells need glucose or ketone bodies, where as Red Blood Cells need only Glucose. Generally blood glucose initially maintained by fed state for 1 to 4 hours called absorptive state, next 4 hours from the end of absorptive state  is called post absorptive state, 10 hours after meal and until 18 hours is referred as fasting state. Prolonged fasting starts from 19 hours after food intake and until 72 hours. Starvation starts after  72 hours of food intake. The rate of blood glucose use by tissues in our body is ~ 2 mg/kg/min in post-absorptive state. When glucose concentration decrease below 75 mg/dl, Epinephrine increases the releases of glucogan from alpha cells and decreases insulin release from beta cells of pancreas favoring increased degradation of glycogen in the liver and skeletal muscle, and Hormone Sensitive Lipase increases lipolysis by degrading Triaclglycerides from adipose tissue and increase gluconeogenesis in the liver.The aim of this review is to analyse biochemically and interpret the metabolism during exercise while fasting. Many health benefits were noted that include lower blood sugar, increases  body's production of human growth hormone, and increases the amount of testosterone if regular exercise is done during fasting. Complete fasting for a period.