Role of Steroids in COVID-19

Abstract

In March 2020 covid-19 declared as global pandemic worldwide and threatens the health of people. Covid-19 affects the people of all age groups. It is a positive single strand RNA virus, which have a high ability to modify its structure. Various therapies used for the treatment of corona virus, but does not have any significant effect. In the 2^nd wave of covid-19, steroids used for providing the symptomatic relief to the patients by mitigating the inflammatory response, especially in lungs. Steroids help to control the dysregulation of immune system. The main objective of this study is to review on the role of steroids in covid-19 patients. This study includes the mechanism of action of steroids, to control the effect of corona virus, uses of steroids, duration and timing of steroids, their interactions with other drugs and the common ADR’s or side effects observed in covid-19 patients. The other main objective of this study is to review the effect of steroids in hospitalized (require oxygen support or ventilators) and mild symptomatic patients.