Influence of a Short-Action Inhibitor on the Course of Chronic Heart Failure

Abstract

During the chronic heart failure occurs an intensified production of aldosterone, which results in the retention of natrium and water. The inhibitors ACF dilate renal vessels and increase renal blood flow that contributes to the amplification of diuresis and natriuresis. In addition, these drugs decrease aggregate peripheral vascular resistance, arterial pressure and increase cardiac output. This article demonstrates the impact of inhibitors on the improvement of microcirculation and decline of platelets aggregation in patients with chronic heart failure.