Remineralising Potential Of Dentifrice Reinforced With Nanohydroxyapatite: A Systematic Review

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Parvathy Harshan, S. Shreelakshmi , Sindhu, Bharathwaj , Dinesh, Rajmohan , Prabu. D

Abstract

Background: Nano-dentistry is an extravagantly advancing field towards the diagnosis and treatment of diseases like dental caries, oral infections, gingival, and periodontal problems. Dental caries being the most frequently encountered dental problem, needs a minimally invasive method of treatment. Hydroxyapatite is the major component of the tooth structure. Hence replenishing it can help tackle dental caries. For this purpose, various studies on nanohydroxyapatite are being conducted to assess its remineralising capacity to prevent or remineralise carious lesions.


Aim: To scrutinise the remineralising potential of dentifrice reinforced with nanohydroxyapatite in enamel lesions.


Study Design: A systematic review on in-vitro studies done using dentifrice incorporated with nanohydroxyapatite to gauge its remineralising capability in early enamel lesions was carried out. Various scientific electronic databases were searched, and 583 articles were obtained, among which 7 were included in this study based on specific selection criteria for further analysis.


Results: 7 in-vitro studies were included in this systematic review. Among these, 5 studies showed that nanohydroxyapatite dentifrices had a superior remineralising capability on artificially made enamel lesions compared to other available agents, hence, bringing us closer to a minimally invasive world of treatment.


Conclusion: Minimally invasive dentistry is taking over the conventional modalities in this modern world. Nano-hydroxyapatite incorporated into dentifrices showed superior strength and better remineralisation potential than other commercially available agents and can be used to manage enamel lesions early.

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Parvathy Harshan, S. Shreelakshmi , Sindhu, Bharathwaj , Dinesh, Rajmohan , Prabu. D. (2021). Remineralising Potential Of Dentifrice Reinforced With Nanohydroxyapatite: A Systematic Review. Annals of the Romanian Society for Cell Biology, 18887–18905. Retrieved from http://annalsofrscb.ro/index.php/journal/article/view/8419 (Original work published June 30, 2021)
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