Histo Pathological Study Of Malignant Tumours Of Lung-An Observational Study

Abstract

TheCarcinoma of the lung is of varied variety based on histopathology. The precise identification of tumors is imperative to initiate specifictreatment under modern therapeutics measures. It is increasingly being recognized in India due to unabated smoking habits and urbanization. The present study includes all the malignant lesions of the lung,slides and blocks with histologically proven lung malignancy in the department of Pathologyin JJM Medical College Davangere. Cases were categorized based on new classification of lung tumoursas per WHO.In all25 malignant lesions of the lung was recorded, ofwhich 13(52%) were biopsies and 12 (48%) were lobectomy specimens. The most common was squamous cell carcinoma (40%)significantly correlated (p=0.001, odds 7.45) withmean age group of 59.52years. Most of the patients were in 6^th decade, with male predominance. The common chief complaints presentedwere, cough with hemoptysis, chest pain and breathlessness, withsmoking as the most commonlyassociated risk factor.The other lesions encountered include,large cell carcinoma4(16%), adenocarcinoma2(8%), small cell carcinoma2(8%), carcinoid tumours14(%), unclassified tumours3(12%), pleuropulmonary blastoma1(4%) and metastatic tumours2(8%). Metastatic tumours were seen secondary to gestational choriocarcinoma; lung tumours are known for histologic heterogeneity and composed of different histological types and subtypes. Light microscopy examination is sufficient to diagnose lung cancer virtually in all cases, with a need for histochemical stains and immunohistochemistry.Limited histologic types weredifferentiated inpediatric tumours and small cell carcinoma of the lung.