Invitro Biological Studies and Characterisation of Schiff Base Complexes of Co(Ii), Cu(Ii), Ni(Ii) and Zr(Iv) Using Dfmpm and 2,2-Diphenylethanamine

Abstract

This article evokes that cardanol, the important component obtained from cashewnut shell liquid (CNSL), plays a pivotal role in the synthesis and enactment of variety of novel compounds of futuristic application .Cardanol transfigures into an aldehyde, di - a- formylmethoxybis(3-pentadecenylphenol) methane (DFMPM) as per earlier methods . The synthesised aldehyde was used to prepare Schiff base ligand by using 2,2-diphenylethanamine, which on treatment with Co(II), Ni(II), Cu(II) and Zr(IV) metal salt solutions forming complexes.  The prepared complexes were characterised by UV- visible, IR and NMR spectroscopy. The surface morphology of the crystals were  studied by SEM and XRD. The  studies such as elemental analysis, melting point, conductivity, metalion intake, antibacterial, antifungal, anticancer, DNA cleavage,  larvicidal, anti-inflammatory and insecticidal were conducted. The studies confirmed hexacoordination in the Co(II), Ni(II) and Cu(II)  complexes and octacoordination  inZr(IV) complex. Other studies indicated that the complexes were good biological agents and they showed a ray of hope in their usage as pharmaceutical agents.