The Role of Cytokine Regulation in Obstructive Syndrome of Atypical Genesis in Children

Abstract

The article presents a review of the literature on the significance and role of cytokines in the course of the disease, their impact on the immune system in acute obstructive bronchitis. The relevance of the problem of acute obstructive bronchitis is associated with the frequency of bacterial complications, the development of life-threatening conditions due to its prevalence in viral infections in children, as well as the presence of atypical bacterial pathogens Acute obstructive bronchitis occurs rather frequently in practice of pediatrician. In many cases pulmonary pathology manifested by bronchial obstruction occurs in early childhood. The disease is more common in young children (20.1%) and more than half of children (57.5%) have two or more recurrent episodes of obstruction. The complexity of etiology and pathogenesis of acute obstructive bronchitis makes the hypothesis of multifactoriality of this pathology most probable. Due to the increasing prevalence of this pathology, further study is an important problem, the solution of which will contribute to the formation of fundamental ideas about the disease.