A Physiological and Histopathological Study on the Protective Effect of Aqueous Leaves Extract of Moringaoleifera against Cisplatin Toxicity in Rats

Abstract

This study aims to determine the amount of protection of the aqueous extract of Moringaoleifera leaves grown in Iraq-Ramadi against the drug cisplatin used in the medicament of cancer. The test animals were split into six groups and given different doses with aqueous extract, and intraperitoneally injected with cisplatin. The results indicated that the aqueous extract reduced the hepatotoxicity and nephrotoxicity resulting from cisplatin injection by analyzing liver enzymes and kidneys' functions physiologically and histologically.