Comparative Evaluation of High Pressure Carbon Dioxide with Low Pressurecarbon Dioxide for Hemodynamic Changes and Pain Symptoms Inlaparoscopic Cholecystectomy

Abstract

Introduction: Hemodynamic changes and pain symptoms are influenced byvolume and pressure of CO2 in laparoscopic cholecystectomy (LC). The studyaimed to compare the above parameters in the low pressure (<8mm Hg) andstandard pressure (12-14mmHg)LC.

Methods:Arandomised,doubleblindstudywasdoneon80patientscategorised into 2 groups.Group A encompassed patients undergoing Lowpressure LC (<8mm Hg). In group B, Standard pressure LC (12-14mmHg) wasdone. Blood pressure, liver enzymes and pain was assessed in different timeintervals.SPSS21wasused toanalyse thedata.

Results: Difference in both systolic and diastolic pressure of Group A andGroup B was seen to be statistically significant. ALP was the only liver enzymeshowed significant difference between the groups at p =0.032. Abdominal andshoulder tip pain exhibited significant difference amongst the group even at 24hours atpvalue at0.037and0.027respectively.

Conclusions:Itconcludesthat lower pressure pneumoperitoneumseemstohave significant effects on blood pressure; both systolic and diastolic, liverenzymesandshoulderpainascomparedtostandardpressurepneumoperitoneuminpatients undergoingLC.