Aspirin Resistance in Patients with Ischemic Stroke: Study at a Tertiary Care Teaching Hospital

Abstract

Aspirin is utilized in ischemic stroke treatment. Notwithstanding, a few patients are not receptive to the antithrombotic activity of aspirin. In this way close by of intense stroke management, secondary prophylaxis is vital. As far as drugs are concerned aspirin is the most common drug used for the secondary prophylaxis. In spite of these different measures there are repeats in numerous patients. Numerous factors have been considered answerable for causing such repeats and aspirin resistance is one of them. The point of this investigation was to evaluate the prevalence of aspirin resistance in Ischemic Stroke patients.This study was conducted in the ischemic stroke patients admitted to the OPD at department of cardiology and Emergency medicine over a period of One year. The study comprised of 38 consecutive patients of ischemic stroke admitted in our wards. All patients with ischemic stroke received standard treatment with non-enteric coated Aspirin 150 mg per day at least for 7 days after which study for platelet function to assess aspirin resistance was performed.Prevalence of Aspirin resistance in our study was found to be 23.7% and this was more prevalent among elderly patients. In light of aftereffects of this investigation we reasoned that aspirin resistance exists. Anyway without any standard definition and best quality level tests accurate predominance and its part in stroke repeat is as yet a matter of examination.