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Stroke is a prevalent public health issue whereby stroke requires long-term care either at a primary care centre or home. Long-term care may jeopardize the Quality of Life (QoL) and financial aspect of the patient and caregiver as they need to visit the outpatient clinic and rehabilitation centre regularly. In recent year, home-based care is more favourable among the patient. However, in Malaysia study comparing the outcome of the primary care centre and home-based care specifically from the perspective of QoL and cost is still lacking. This is especially involving the patient and caregiver. Hence this study attempts to develop the conceptual framework in analysing the cost and QoL quality of life for caregivers and post-stroke patients receiving home care and primary care.