Prevalence of Class-1 Integron Genes among Multi-Drug Resistance of Uropathogenic Escherichia coli from Pregnant Women

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Muna Abdul-Imam Al-Mazini

Abstract

The first aim of this study was determination of the prevalence of urinary tract infections (UTI) among pregnant women in Basra- city. They were diagnosed by VITEK-2 System. Escherichia coli was the major pathogen (52.5%) causing UTI, followed by less percentages pathogens throughKlebsiella pneumonia, Staphylococcus aureus, Pseudomonas aeruginosa, Staphylococcus epidermidis, proteus mirabilis and Enterobacterspp. The second aim was investigation the frequency of integron genes intI-1, intI- 2 and intI-3 of E. coli strain and their association with antibiotic resistance used in this study. A total 42(52.5%) E. coli isolates from urine samples were tested againt to 10 different antibiotics and that most strains (90.4%) were as Multi- Drug Resistances at significant differences (p˂ 0.05). Among 42 isolates of MDR- E. coli , 31(74%) had the integron genes. The most common of strains had integron genes class-1 (intI-1) at percentage 25(60%), wherease integron genes class-2 (intI-2) and class-3 (intI-3) at percentages 6(14%) and (0%) respectively. Therefore, preventive strategies are necessary to restrict further dissemination of resistant strains.

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How to Cite
Muna Abdul-Imam Al-Mazini. (2021). Prevalence of Class-1 Integron Genes among Multi-Drug Resistance of Uropathogenic Escherichia coli from Pregnant Women. Annals of the Romanian Society for Cell Biology, 11386–11391. Retrieved from http://annalsofrscb.ro/index.php/journal/article/view/3917
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