STUDY ON SERUM HEPCIDIN LEVEL IN CHRONIC KIDNEY DISEASE

Abstract

AIM

The present study was to estimate and to compare serum hepcidin levels in controls and patients of chronic kidney disease and to check the correlation of hepcidin to anemia and inflammation in chronic kidney disease.

OBJECTIVES

Estimate serum hepcidin levels in controls and patients with chronic kidney disease. Determine and correlated to markers of anemia and inflammations in chronic kidney disease.

MATERIALS AND METHODS

Serum Hepcidin was estimated along with other biochemical parameters such as serum Urea, Creatinine, Iron, Ferritin, Transferrin, Total iron binding capacity (TIBC), hsCRP and Hemoglobin.

RESULTS

Hepcidin could be a prognostic marker in the clinical outcome of CKD especially in the progression of CKD.

CONCLUSION

Serum hepcidin correlated positively with markers of iron status (iron and ferritin) in the CKD group