Bio-Green Synthesis Silver Nanoparticles Mediated by Cloves Seed Extract (Syzygium Aromaticum) and Antibacterial Activity on MDR Staphylococcus Aureus

Abstract

A systemic methodology was introduced in this study to investigate the enhanced antibacterial and anti-biofilm effects of broad-spectrum antibiotics with and without AgNPs. To that end, we synthesized AgNPs using cloves seed extract in an environmentally friendly manner (Syzygium aromaticum). The synthesized AgNPs were then characterized using a variety of analytical techniques. The AgNPs particles were uniform in size, with an average dimension of 32.8 nm. Furthermore, the antibacterial potency of the selected antibiotics has improved. AgNPs were discovered to be present in science. Tetracycline is a drug that is used to cure Gram-positive bacteria such as Staphylococcus aureus. Fortunately, the combination of sublethal concentrations proved successful. Antibiotic use in conjunction with AgNPs has resulted in a significant increase in antibiotic resistance.