The Role of Artemisia Herba-Alba in Treatment of Kidney Disorders that Induced by Cell Wall of Enterobacter Cloacae Rats

Abstract

      The current work was aimed to exhibited the role of A. herba-alba  to enhance the antioxidant state after treated the rats with cell wall of E. cloacae. The work utilized 20 rats that distributed to five groups (each group consist 5 rats); control group that received normal saline, rat received (orally) with 50u/ml of cell wall extract. rat received (orally) 50u/ml of cell wall extract and treated with 50mg/kg of leaves extract. Rat received (orally) with 50u/ml of cell wall extract and treated with 100mg/kg of leaves extract. The findings revealed significant (P < 0.05) elevate in MDA with reduce in levels GSH and catalase in rat received (orally) with 50u/ml of cell wall extract compare with control rat. The findings of treated rats exhibited non-significant (P < 0.05) changes oxidative state compare with control rat. Histological, kidney slides exhibited thickening wall of blood vessels, hemorrhage with fibrosis in kidney of rat received (orally) with 50u/ml of cell wall extract. After treatment with leaves extract, kidney back to semi-normal state. It was concluded that A. herba-alba has antioxidant activities.