Histopathological Effects Resulting from the Experimental Infection of Laboratory Mice Affected with Amoebic Dysentery and its Treatment with Camel's Milk and Urine

Abstract

The study was carried out by isolating the Entamoeba histolytica cysts from the excrements and causing experimental infection in laboratory mice with amoebic dysentery by giving 1000 mature cysts as an oral dose. After two weeks of induction, the treatment was attempted using camel urine and milk separately and in doses 0.25, 0.5, 0.75 ml per treatment and comparing it with a group treated with Flagyl drug. The results of histological study showed occurrence of histopathological changes in rectum of laboratory mice, which were represented in the infectious groups by appearance of nodular lymphatic infiltration and necrosis and cellular abnormalities. As for the groups treated with camel milk and urine, they showed a marked improvement represented by the lack of histopathological effects such as necrosis, cellular leaching and cellular degeneration. The best results were with the therapeutic dose of the concentration 0.75 ml mixed with camel milk and urine.