Evaluation of Therapeutic and Protective Influences of Camel Milk Against Gamma Radiation– Induced Hematotoxicity, Hepatotoxicity and Nephrotoxicity in Albino Rats

Abstract

Camel milk so called white gold of the desert is more similar to human milk than any other milk. Fresh camel milk provides particular health benefits depending on the bio-effective fractions in it. Aim of the work is investigating protective effects of camel milk in gamma irradiated abino rats was investigated. Methods of this work: Ninety six of Sprague Dawly healthy adult male albino rats were utilized, classified and labeled in 16 groups. Biochemical determinations of hepatological and nephrological parameters were determined from collected blood samples. Histo-pathological examination were done for liver and kidneys. Results: IRR caused significant changes in kidneys and liver functions as well as protein profile. Serum levels of ALT, AST and ALP increased significantly, also serum levels bilirubin, urea, uric acid and creatinine levels were elevated, whereas serum protein profile (total soluble protein, albumin and globulin levels) was decreased paralleled with dose dependent.Concerning hematological parameters, IRR resulted in a significant decrease in the values of Hb, RBCs count, platelets count, MCH and HCT %, while insignificantly changed the value of MCV, MCHC and WBCs count. These changes were paralleled with the dose dependent.Camel milk treatments in the IRR rats have improved their irradiated status and attenuated the alteration of liver and kidney functions as well as, hematological abnormalities associated with IRR harmful effect.