Pattern of Multi Drug Resistance with Biofilm Formation among Klebsiellapneumoniaisolated from Fecal Samples of Diarrheal Iraqi Patients
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Abstract
Klebsiella pneumonia(K. pneumonia ) is an opportunistic pathogen, Most of its cause of health care associated infections (HAIs) and possess high stages of antibiotic resistance. Thesemicro organisms are great recognized for his or her capacity to provide biofilms. The cause of this take a look at is to decide the sample of antibiotic resistance and the capacity to provide biofilms of K. pneumoniaefrom fecal samples of diarrheal sufferers in a few Hilla hospitals. Bacteria collected was isolated from patients with diarrheal cases in some Halli hospitals form the period ( September-October 2020). All of them were collected from both sex and differenced ages (<10- 60) years and it isolates were cultured and diagnosed by ordinary method as well as by the Vitek2 system also, Antibiotic sensitivity test(AST) were done using Vitek2 system and biofilm production detected by Congo-red agar method. From one hundred fecal samples, 75(75%) K. pneumoniae isolates were obtained from 25 male (33.3%) and 50 females (66.6%) . All bacteria isolates were resistant to Ampicillin at (100%) and more sensitive to Ertapenem, Imipenem, Piperacillin/Tazobactam,Amikacin,Tigecycline at(100%).50( 66.6%) MDR isolates were obtained from K. pneumoniae and 52 (69.3%) biofilms products isolates with 23 (30.6%) non-biofilms were produced. Significant difference in (p <0.05).from the current study, Most of theK. pneumonia bacteria isolates have proven resistant to a wide range of tested antibiotics and are biofilm-producing. This was a strong correlation between MDR ability and Biofilm formation in K pneumoniae.