The State of Humoral Immunity in Women after Cesarean Section with Postplantar Intrauterine Contraception

Abstract

The study of the role of factors of the immune system remains one of the important areas of modern medicine. Humoral immunity factors - interleukins - 1 and 8, as well as circulating immune complexes are the main participants in the immune mechanisms responsible for the compensatory response of immunity during surgical interventions and the introduction, in particular, of an intrauterine contraceptive. The protective and adaptive functions of the immune system are carried out thanks to the cytokines - IL-1 beta and IL-8. So, the intrauterine administration of a contraceptive to practically healthy women after surgical delivery did not affect the state of the local immune system, as well as the general condition, without causing inflammatory processes.

For the first time, studies of the humoral factors of immunity were carried out, which determine the development and formation of protective compensatory-adaptive reactions. It has been shown that the cytokines IL-1β and IL-8, as well as the CIC, have important not only diagnostic, but also prognostic value in operative delivery and the introduction of an intrauterine contraceptive. The IL-1β / IL-8 ratio turned out to be an important prognostic marker. Thanks to which it is possible to predict the level of compensatory, with a pronounced suppression of the index - the inflammatory process. Moreover, postplantar intrauterine contraception leads to certain changes in the balance of immunity mediators, which should be proportional to the degree of the inflammatory process.