Features of the Functioning of the Third Type of Interferon - Interferon Lambda in Viral Hepatitis

Abstract

In chronic viral hepatitis, there is a pronounced role of the IFN-lambda genotypes, which consists in genetic predisposition, and in achieving a stable virological response in patients with chronic viral hepatitis C against the background of treatment with drugs of genetically engineered interferon and ribavirin.

In the literature there are isolated data on the study of IFN-28B and its gene in chronic viral hepatitis B. We think that research in this area should be continued. Gene polymorphisms should be determined, which we are sure will allow predicting the probability of achieving a persistent virological response with a sensitivity of 65% and a specificity of 78%.