The Correlation among Osteoporosis, Calcium-Phosphore Metabolism and Clinical Symptoms of Main Disease in Patients with Rheumatoid Arthritis

Abstract

110 patients (25 women, 55.5%, 20 men, 44.4%) underwent clinical, laboratory and instrumental examinations to determine parameters of acute phase proteins, iron metabolism blood and bone tissue density in patients with rheumatoid arthritis. So, Physical examinations allowed to detect the specific clinical signs for OP in 17.2–48.0% of patients. Computed tomography with X-ray densitometry showed that 40% of patients had grade I of osteoporosis, 26.7% - grade II of osteoporosis, and 33.3% - grade III of osteoporosis. Hypocalcemia was characteristic of patients with OP. Chronic anemia (CA) was found in 53.7% of RA patients, iron deficiency anemia (IRA) in 39.6%, and both of them in 3.1%. CA leads to aggravation of the main disease, severity of anemia, and it is characterized by profound changes of hematological parameters.