Pharmacological Investigation of Lawsonia Inermis L. Seed Extracts: An Invitro Study

Abstract

Lawsoniainermis L. belongs to branched glabrous shrub. They are mainly cultivated for its leaves. The seeds, bark, roots, flowers also are used in traditional medicine. In the present study the hexane and methanolic extracts of L.inermis seeds were analysed for phytochemical analysis, antioxidant, antibacterial and anticancer activites. The preliminary phytochemical analysis in hexane and methanolic extracts showed the presence of compounds such as carbohydrates, proteins, flavonoids, tannins, phenolic compounds, alkaloids, terpenoids, and fatty acids. The free radical scavenging activity using DPPH assay showed that the methanolic extract possessed higher antioxidant potential. The antibacterial activity assessed using the seed extract showed activity against gram negative bacteria and the zone of inhibition was prominently seen in the methanolic seed extract. The anticancer activity using MCF 7 cell line exhibited promising results and the percentage of cell viability decreased after treated with methanolic seed extract. Thus the study proves that L.inermis seeds have phenomenal medicinal values to be explored in the future.