Role of Some Cytokines in Pathogenicity of Toxoplasmosis in Aborted Women in Karbala,Iraq

Abstract

210 blood samples were collected for pregnant women who aborted with toxoplasmosis and those who aborted for other reasons during the first trimester of pregnancy at the Obstetrics and Gynecology Teaching Hospital in the city of Karbala during the period 7/1/2021 until 2/22/2023. The required information was recorded according to a special questionnaire form prepared in advance. For this purpose, the results of the rapid examination, RAPID TEST, out of 210 aborted women, showed that 60 of them were infected with toxoplasmosis, a percentage of 28.5%, while 150 women aborted for other reasons, out of 210 aborted women, a percentage of 71.4%, were negative (serum) and not infected with Toxoplasma gondii.The results of the examination of immunological indicators showed that there was a significant increase in TNF-α cytokinetic concentrations in patients aborted with toxoplasmosis 13.18±3.49 pg/ml compared with the mean and standard error 8.45± 1.89 and 4.18±0.83 for each of the patients aborted for reasons Other women control.The results did not record any significant differences in the level of cytokinetic TGF-β for the patients who aborted with toxoplasmosis and the patients who aborted for other reasons, respectively 27.18±4.63 and 25.29±2.16 compared with the control group, as the rate was recorded at 4.66±0.78