A Short Review on Biological Evaluation of Novel Schiff Base Complexes with Divalent Transition Metals

Abstract

Schiff's bases are appropriate ligands that can be produced by condensing 1^o amines with C-O groups such as CHO and =O. This process of condensation leads to the production of Schiff's bases. Due to their involvement in a wide variety of biological activities, these compounds are of great importance to the pharmaceutical and medical sectors. The great majority of them have antibacterial, antifungal and anticancer properties. Under the majority of experimental conditions, Schiff's base ligands can react with metal salts to produce metal complexes. A lot of research has been done to try to figure out how Schiff's base ligands change the biological activity of transition metal complexes. This article provides a summary of the biological actions of new Schiff base compounds incorporating divalent transition metal.