Strokes Outcome Determinants in Pakistan Primary Stroke Center

Abstract

Pakistan is among the leading Asian countries with high stroke mortality. The public perception & the knowledge level about the stroke outcome determinants are not cognizant. The primary aim of the study is to assess stroke outcomes determinant in Pakistan Institute of Medical science, Pakistan. This study assessed/evaluated a) demographic b)clinical c) outcome data of the patients with a) Ischemic stroke b) hemorrhagic stroke c) transient ischemic stroke (TIA) d) intra-cerebral hemorrhagic stroke (ICH), e) in-hospital mortality  f) functional outcomes, admitted to the center along with the patient’s demographic. Binary logistic regression & univariate analysis was performed for the analysis of the data .One hundred eighty four (184) stroke’spatients were included in the study, 52.20% being male with the 66.8±15.7 years means age. The stroke variations among the enrolled patients was; IS:59.2%, TIA: 29.6%, ICH:11.10%. This study report that ICH cases were associated with greater severe symptoms, poor prognosis & poor functional outcomes. The determinants of the poor functional outcomes were lower GCS (Glasgow coma score), higher NIHSS & reduced O₂ saturation level. Regarding the mortality determinant, visual symptoms presence was found to be the most important. Stroke outcomes determinants & stroke mortality found in this study is not significantly different from those found in the developed countries. Stroke prognosis is crucial in order to understand stroke’s burden in the developing country like Pakistan.