Anticancer and antioxidant activity of silver nanoparticles of calotropis gigantea

Abstract

Natural products, as a pure compound or as a standardized plant extractsProvide unlimited opportunities for new drug lead because of the unmatched availability ofChemical diversity. Curative property of the medicinal plant isattributedtothevariouschemicalsubstancesofdifferentcompositionthatariseas secondary metabolitesandgetlocalizedinoneormorepartsoftheplant.Thesecomplexphytochemicalscouldplayavital roleinminimizingthe development ofdrugresistance. Cancer is an abnormal growth of cells that grows and spreads through uncontrolled celldivision (Fig 2). These ‘malignant’ cells may invade other tissues and spread (metastasize) to moredistant parts of the body. Cancer is not one disease but a group of more than 100 distinct disorders.Itisthe world’s secondbiggestkiller aftercardiovascular disease andwas responsible for thedeath of 7.6 million people in 2005.In our study pharmacological screenings of C. gigantea revealed its medicinal potential and represents as a valuable medicinal plant with several medicinal properties.