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The sex hormones of women evolved in an unexpected way. As a result, the female body reacts in a number of ways to hormonal changes. As a result of these changes, they are more likely to acquire periodontal disease and show periodontal manifestation. Hormonal effects can be found in almost every type of biological tissue, indicating physiological and pathological alterations.Because gingival tissue contains oestrogen and progesterone receptors, it functions as a sex hormone target organ. Ovarian hormones have been demonstrated to increase the sensitivity to local irritants and induce gingival inflammation. Female sex hormones have an impact on the composition of sub-gingival bacterial plaques as well as a woman's immune system.Inadequate dental hygiene and hormonal imbalances prevalent in female patients at different periods of life boost the oral tissues' sensitivity to plaque and other local variables, aggravating the condition.