Study of Seru for Some Immune Factors in Thyroiditis Disease Patients

Abstract

Abstract. thyroiditis disease is an autoimmune inflammationIt has genetic, clinical, pathological, and immunological features, and it goes through alternating phases of healing and relapse.The aim of this study was to assess the immunological status of some Iraqi Thyroiditis patients   . The present study was conducted on a groups of patients . This study was conducted for a period from the beginning of October 2020 to the end of January 2021, as blood samples were collected from patients with thyroiditis, as well as healthy people from  Baquba Teaching Hospital and Al-Batoul Hospital Education Feminine & Pediatric in DiyalaGovernorateaged 27 female and 3 males  healthy participants included in this study as a control group. Their ages ranged between (18-45) years.Hyperthyroidism Group 25 female and 5 males patients.Their ages ranged between (23-60) years.Hypothyroidism Group 30 female patients. Their ages ranged between (21-60) years. The research looked into the relationship between immunological detection of Immunoglobulin E cellular motility and the ELIZA technique.The current study's findings revealed a significant increase in the level of Immunoglobulin E concentration in the serum of patients with  (438.64 ± 52.54) ng/m1 when  compared with control group (365.61 ± 19.13 ) ng/m1.at a probability level (P< 0.026). While  the result  revealed that there was no significant decrease in serum Immunoglobulin E level in hypothyroidism group (339.35 ± 13.24) ng/m1 and  when  compared with the control group (365.61 ± 19.13 ) ng/m1 . These findings suggest that Immunoglobulin E might have a role in etiopatho genesis of Thyroiditis disease