The Study Effect of Infected Wheat and Rice (With Aflatoxin and Benzoquinone) On Rat Liver

Abstract

The current study aimed to estimate the physiological and histological effect of rat liver that feeding of infected wheat and rice. Samples were collected in Kirkuk city, and included Kirkuk silo, Riyadh Al-Makhzani complex, and Taza Grain Center of the General Company for Grain Trade, one of the branches of the Iraqi Ministry of Trade.10 samples of wheat and rice were collected from 2 kg for each sample of grains for the period from 1-9-2019 until 22-9-2019. The rats were randomly divided into 6groups(6 rats in each treatment). It included the following:The first treatment (T1): a group of control rats for normalwheat, the second treatment (T2): a group of control rats for normal rice, the third treatment (T3): a group of rats given orally 50% of normalwheatand 50% of the infected wheat contains different concentrations of aflatoxinand benzoquinone. The fourth treatment (T4): the group of rats given orally 25% of normalwheat is and 75% of the infected wheat contains different concentrations of aflatoxinand benzoquinone. The fifth treatment (T5): The group of rats given orally 100% to the infected wheat contains different concentrations of aflatoxinand benzoquinone. The sixth treatment (T6): 100% infected rice.The current results showed that there were significant (P≤0.05) differences between the study groups. The current results group given infected 100% wheat showed a significant increase in AST, ALT and ALP levelscompared with control group. On the other hand, it was observed that the group given infected 100% rice showed a significant increase in the levels of AST, ALT and ALPcomparedwith control group given normal rice. Histological study, different histological lesions were diagnosed including degeneration of hepatocytes, fibrosis with lymphocytes infiltration and thickening wall of central veins.