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Now a days when whole world facing challenges due to COVID-19 viruse to prevent from it scientists made some vaccines and that vaccines required cold conditions to store. So that we made a mini portable cooling box which helps to carry that vaccines to the remote places where conventional cooling system may not be reach. Solar cooling box using thermoelectric module is going to be one of the most cost effective, clean and environment friendly system. This paper does not need any kind of refrigerant and mechanical device like compressor, prime mover, etc for its operation. The main purpose of this project is to provide refrigeration to the remote areas where power supply is not possible.