Synthesis and Characterization of Copper (II) Complexes with Various Ligands and its Larvicidal, Antifeedant and Mosquito Larval Growth and Regulation Activities

Abstract

The catalyst free one-pot synthesis of Copper complexes with various organic ligands by using ethanol as a solvent. This method offers efficient and mild reaction conditions. The synthesized complexes were described by UV- Visible and FT-IR spectroscopy.The synthesized complexes are also evaluated for larvicidal, antifeedant, and mosquito larval growth and regulation activities. Complex1b was highly active against Culexquin quefasciatusthan complexes 1aand 1cwith the LD₅₀ value of 45.28 µg/mL. The complexess 1aand 1cwere less active against Culexquin quefasciatus with the LD₅₀ values of 69.83 and 84.73 µg/ml respectively. Complex 1a produced 66% mortality in 24hr at 100 µg/ml againstOreochromis mossambicus in antifeedantscreening and also toxicity was measured as death percentage at 24hr. Complex 1b produced 60% mortality in 24hr at 100 µg/ml. Among the synthesized complexes 1a-1c the complex 1a havinghightoxicity with the LD₅₀ value of 69.57 µg/ml.