Comparison of Single-Step Random 75g Dipsi Criteria with Fasting 75g Iadpsg Criteria Oral Glucose Tolerance Test in Diagnosis of Gestational Diabetes Mellitus

Abstract

Objective:To compare random 75 g oral glucose tolerance test (OGTT) by the Diabetes in Pregnancy Study Group of India [DIPSI criteria] with fasting 75 g OGTT International Association of the Diabetes and Pregnancy Study Groups criteria [IADPSG criteria] in diagnosing GDM and compare outcomes of patients diagnosed with these two criteria.  Materials and Methods:Pregnant women with gestational age between 24-42 weeks, attending antenatal OPD were divided into two groups; Group-I[DIPSI criteria] and Group-II[IADPSG criteria]. Two hour glucose ≥140mg/dl [DIPSI] and any one of fasting ≥92mg/dl; one hour ≥180mg/dl and two hours ≥153mg/dl [IADPSG] were diagnosed as GDM and maternal and perinatal outcomes followed in GDM positive cases.Results: Three hundred patients (n=150 in each group) were enrolled. There no significant difference in the mean age (p=1.00), multigravida status (p=0.729) or lower socioeconomic status (p=0.726) between two groups but mean gestational age (35.99 vs 35.17 years; p=0.045) and mean BMI (23.95 vs 22.88 kg/m2; p=0.001) were higher in DIPSI group. Incidence of GDM was 18 (12%) and 17 (11.3%) with DIPSI and IADPSG criteria respectively.Seven (38.9%) and five (29.41%) patients in DIPSI and IADPSG criteria had maternal antenatal complications (p=0.854). Fetal antenatal complication rate was three (16.7%) and two (11.8%) in DIPSI and IADPSG groups respectively (p=0.679). Newborn complications rate was two (11.1%) in DIPSI and four (23.5%) in the IADPSG group (p=0.33).  Conclusion:In our study, there was no significant difference in the rate of diagnosis of GDM or maternal and perinatal outcomes in patients diagnosed with DIPSI and IADPSG method. DIPSI was a suitable, reliable and feasible method for diagnosis of GDM.