Comparison between Use of Perforated and Non-Perforated Collagen Membrane Using Guided Tissue Regeneration Technique for Management of Infrabony Defects – A Clinical and Radiographic Study

Abstract

Aim: The study aimed to evaluate the effectiveness of perforated collagen membranes in comparison with non-perforated collagen membranes for guided tissue regeneration of infrabony defects.
Materials and Methods: A total of 30 intrabony defects that is 30 sites were randomly selected for the study. 10 infrabony defects each were treated using open flap debridement with the placement of nonperforated membrane, using open flap debridement with a placement perforated membrane and using open flap debridement in Groups A, B and C.
Results: Intragroup comparison showed statistically significant difference from baseline to 9 months in nonperforated membrane and perforated membrane (p<0.05) for clinical and radiographical parameters. However, there was no statistically significant difference seen with open flap debridement for clinical and radiographical parameters. (p>0.05) Intergroup comparison did not show any statistically significant difference from baseline to 9 months in nonperforated membrane and perforated membrane (p>0.05) for clinical and radiographical parameters.
Conclusion: In conclusion, the present study did not demonstrate any enhanced clinical outcomes when using open flap debridement with the placement of nonperforated membrane, with a perforated membrane and using open flap debridement alone procedures.