Evaluation of Intra Placental Vascular Pattern in Postdate Placenta, By Casting and Immunohistochemical Evaluation of Α-Smooth Muscle Actin

Abstract

Placental senescence impairs villous capillaries and intervillous spaces decline, changes in placental vascular structure appear at various stage of pregnancy, many factors act on placental angiogenesis to insure adequate placental vascular function .Study of placental vasculature, and α-smooth muscle actin component of microfilament of contracting cells in villous stemand blood vessels tunics, is of great importance for fetoplacental blood flow assessment, ascontraction and relaxation of myofibroblast regulate inter-villous space volume and control placental hemodynamics.This study aimed to evaluate fetal vascular changes in placental villi, in postdate placenta by casting method and immunohistochemical expression of α-smooth.