A Review on Current Scenario in Drug-Loaded Nanocapsules in Cancer Treatment
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Abstract
Various types of carriers presently available in care of cancer for targeted medicine delivery, each with its own combination of advantages and disadvantages.Polymeric nanocarrier like, micelles, dendrimers, magnetic and gold nanoparticles,liposomes, quantum dots, silica nanoparticles, polyethylene glycol, and carbon nanotubes were given special consideration.To achieve controlled drug release and effective delivery of drug, nanocapsule of dispersed polymercan be used as a drug transporter that is nanoscale in size.The main determinants, stability of dispersion are the surfactant structure and the outer coating shape.The structure and configuration of capsule walls have a major impact on release and deterioration characteristics of the capsules.The nanocapsule size range is between 1 to 100 nm.There are major methods for producing nanocapsules arepolymerization, interfacial polymerization, arc discharge,emulsion polymerization andencapsulation of nanocapsule method.Measurement of capsule surface, Capsule radius distribution, thermal or chemical decomposition, capsule membrane thickness and permeability are the most significant capsule parameters.