Effects of Ascorbic Acid Supplement and Furdivita extraction on Hematological Parameters, liver function tests and histopathological changes in Rabbits liver

Abstract

The water-soluble micronutrient Ascorbic (vitamin C) is an essential for several biological activities. Ascorbic acid has a long history of usage in conventional processes that regulate the production of free radicals with antioxidant effects. Free radical levels in cancer cells have been documented to be high. The research aimed at studying hematological of the adult male rabbits.Ascorbic acid (40mg/kg/BW/day for 12 weeks). The influence of ascorbic acid at the termination of a 12 week clinical cycle on complete counts of erythrocytes (CBR), hemoglobin (HB), cell-packed volume (PCV), total WBC,MCV, MCHC, mean plasma glutathione-s-transferease (GST), acetyl cholinesterase (AChE), and thiobarbituric acid-reactive substances (TBRS). Ascorbic acid therapy resulted in a substantial improvement (P<0.05) in RBC and WBC, while Hb, PCV, MCV, MCH, MCHC, GSH, AChE behavior were not changed in contrast with regulation. Compared to control community, the TBARS are considerably decreased (P<0.05). Thissearch concludes the addition of a vitamin C supply to food will boost anemia and suppress free radicals in adult male rabbits for a long period. Fordvita is a furan obtained from plant extracts of plant residues Saccharumofficinalis Effect. This extract was found in the tissues of some organs in mice by watering animals at two concentrations (95.22 and 5.5) mg / ml at LD50 and 50 LD at a rate of one, two, and three weeks. The results showed that both concentrations (95.22 and 5.5) mg / ml have the same thing.The effect on infection compared to the control group. After three weeks, results were better with preserving the organs from histological changes in the intestine, liver and spleen. And that the histological effect was less in the spleen than in the liver and intestine. The histopathological lesions found by feeding this plant mixture were strengthened in the livers of rabbits with hypercholesterollemia. In this review, diet consumption of the celery plant is recommended; it can be helpful for hypercholesterol and hepatic disease patients.