The Possiblee of Tuberculosiso Selected Interleukinsa Neurotransmitters among Displaced Iraqi Peoples
Main Article Content
Abstract
Background: Tuberculosis is one of the world’s oldest and most important disseminating infectious disease that still accounts for a high morbidity and mortality among adults particularly in developing countries including Iraq which suffered from migration and displacement of millions of peoples due to series of wars ended by ISIS terror and invasion. Tuberculosis might cause changes in activity of neuro modulating factors as well as in the behaviour of the immunological responses including cytokines at the same time. Methodology: In the current study there were 50 patients (18 displaced and 32 non displaced TB patients) and 40 healthy control.Interleukins-6, interleukin-10, acetylcholine and serrotinin were estimated in the seum of those patients examined. Results: interleukin (IL-6),interleukin(IL-10), serrotinin (ST)and acetylcholine(ACH) concentrations showed various differences individually and/or together with respect to patients origin and gender in comparison to non-TB control individuals. Conclusions: Serum cytokines IL-6, and IL-10 were elevated. Neurotransmitter likes eroton in and acetylcholine were significantly correlated with each other and with cytokines studied which revealed a synergistic effect of tuberculosis on the values estimated of both cytokines and neurotransmitters.